Vietnamese Rapid Acceleration Protocol for Intensifying Drug Therapy in Heart Failure With Reduced Ejection Fraction

NARecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

August 1, 2028

Study Completion Date

January 1, 2029

Conditions
Acute Heart Failure (AHF)Acute Heart Failure With Reduced Ejection Fraction
Interventions
OTHER

High intensity care

This arm follows a structured algorithm for initiating and uptitrating all four pillars of HFrEF oral medications post-randomization (pre-discharge) and during at least 4 visits over 6 weeks post-discharge.

OTHER

Usual care

Patients will be managed by their cardiologist according to their usual practice. Follow-up appointments will be scheduled as per the cardiologist\'s instructions. Participants will return to the recruiting study site for clinical outcome assessment by study investigators at 90 and 180 days post-discharge.

Trial Locations (4)

520000

NOT_YET_RECRUITING

Quang Tri Province Hospital, Đông Hà

700000

NOT_YET_RECRUITING

Thong Nhat Hospital, Ho Chi Minh City

RECRUITING

University Medical Center Ho Chi Minh City, Ho Chi Minh City

880000

NOT_YET_RECRUITING

An Giang Heart Hospital, Long Xuyen

All Listed Sponsors
collaborator

Momentum Research, Inc.

INDUSTRY

collaborator

INSERM UMR-942, Paris, France

OTHER

collaborator

University of Medicine and Pharmacy at Ho Chi Minh City

OTHER

lead

University Medical Center Ho Chi Minh City (UMC)

OTHER

NCT06595290 - Vietnamese Rapid Acceleration Protocol for Intensifying Drug Therapy in Heart Failure With Reduced Ejection Fraction | Biotech Hunter | Biotech Hunter