BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

September 30, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2026

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
DRUG

BTLA inhibitor (JS004)

BTLA inhibitor (JS004):200mg, intravenous infusion , d1, Q3W;

DRUG

Toripalimab

Toripalimab:240mg,intravenous infusion, d1, Q3W;

DRUG

Paclitaxel, Cisplatin

Paclitaxel, 175mg/m2, intravenous infusion, d1, Q3W; Cisplatin, 75mg/m2, intravenous infusion, d1, Q3W;

All Listed Sponsors
lead

Henan Provincial People's Hospital

OTHER

NCT06588335 - BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma | Biotech Hunter | Biotech Hunter