Neurobiological Drivers of Mobility Resilience: The Dopaminergic System - Supplemental Open-Label Arm

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

October 29, 2024

Primary Completion Date

April 3, 2025

Study Completion Date

April 3, 2025

Conditions
Parkinsonian Signs in Older Persons
Interventions
DRUG

Carbidopa 25 mg

Participants will take one 25mg Carbidopa tablet 3 times a day for 10 days.

DRUG

Carbidopa-Levodopa 25/100 mg

Participants will take one 25/100mg carbidopa-levodopa tablet 3 times a day on days 4-6, then increase to 1.5 tablets 3 times a day on days 7-10.

Trial Locations (2)

48105

Domino's Farms, Ann Arbor

48109

University Hospital, Ann Arbor

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of Michigan

OTHER

NCT06587217 - Neurobiological Drivers of Mobility Resilience: The Dopaminergic System - Supplemental Open-Label Arm | Biotech Hunter | Biotech Hunter