Strength Training and Resveratrol

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

June 13, 2025

Primary Completion Date

July 31, 2026

Study Completion Date

August 31, 2026

Conditions
SarcopeniaAnabolic Resistance
Interventions
BEHAVIORAL

Resistance training

After pre-testing, participants will perform full-body strength training three times per week for two 6-week blocks. The acute program variables (sets, repetitions, training frequency) will follow a non-linear periodized, progressive design consisting of muti-joint and single-joint exercises. Exercise stress will be varied by using different exercises and loads. The two training blocks will be separated by a mid-intervention testing week, allowing for the study team to monitor participants' progress, communicate progress to participants to promote adherence, and adjust target loads as appropriate for the second half of the intervention. An additional testing week will follow the second 6-week block.

DIETARY_SUPPLEMENT

Resveratrol 500 mg oral once daily.

Participants will be randomized to consume resveratrol (500 mg) daily for 14 weeks (two 6-week blocks of resistance training \[supervised, full-body, 3 days/week\] + one testing week \[3 days\] following each block) after the pre-testing period. Participants will be provided with 7 days' worth of supplements at a time in pre-filled pill boxes. Pill boxes will be refilled weekly and adherence monitored.

DIETARY_SUPPLEMENT

Placebo

Participants will be randomized to consume placebo capsules (cellulose, visually identical to resveratrol capsules) daily for 14 weeks (two 6-week blocks of resistance training \[supervised, full-body, 3 days/week\] + one testing week \[3 days\] following each block) after the pre-testing period. Participants will be provided with 7 days' worth of supplements at a time in pre-filled pill boxes. Pill boxes will be refilled weekly and adherence monitored.

Trial Locations (1)

79409

RECRUITING

Department of Kinesiology & Sport Management, Texas Tech University, Lubbock

All Listed Sponsors
collaborator

National Strength and Conditioning Association

OTHER

lead

Texas Tech University

OTHER