Understanding Cerebral Blood Flow Dynamics for Alzheimer's Disease Prevention Through Exercise

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

September 25, 2024

Primary Completion Date

January 2, 2025

Study Completion Date

January 2, 2025

Conditions
Healthy AgingCognitive Function 1, SocialCerebrovascular CirculationBlood Flow
Interventions
BEHAVIORAL

Aerobic exercise condition

Aerobic session will last 30 min. The average intensity of the aerobic sessions will be 60-70% of the Maximal Heart Rate. Therefore, participant will perform a continuous moderate intensity aerobic bout of exercise on a cycle ergometer.

BEHAVIORAL

Resistance exercise condition

Resistance exercise will last 30 min at 4-6 RPE (OMNI-Resistance Exercise Scale of Perceived Exertion from 0-10). The bout of resistance exercise will include a combination of upper and lower body exercises using elastic bands and the participants' body weight as the primary resistance. Eight different exercises will be performed per set, with 40 seconds per exercise, for a total of 3 sets. The exercises are based on basic movement patterns and include: glute bridge, front plank, standing face pull, incline push-up, squat, pallof press, walking lunge and seated shoulder press.

Trial Locations (2)

18011

Mind, Brain, and Behaviour Research Centre (CIMCYC, Centro de Investigación Mente, Cerebro y Comportamiento), Granada

18016

University of Granada, Granada

All Listed Sponsors
collaborator

University Hospital Virgen de las Nieves

OTHER

collaborator

Instituto Mixto Universitario Deporte y Salud (iMUDS)

UNKNOWN

collaborator

Centro de Investigación Mente, Cerebro y Comportamiento

UNKNOWN

lead

Universidad de Granada

OTHER

NCT06584656 - Understanding Cerebral Blood Flow Dynamics for Alzheimer's Disease Prevention Through Exercise | Biotech Hunter | Biotech Hunter