Pre-hospital Administration of Fibrinogen in Trauma-Induced Coagulopathy

NANot yet recruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

August 31, 2025

Study Completion Date

December 31, 2025

Conditions
Trauma Induced Coagulopathy
Interventions
DRUG

Fibrinogen concentrate

Patients will be randomly assigned to receive either standard trauma care or standard trauma care plus administration of FC. The standard of care is determined by national guidelines on trauma, elaborated by the National Institute of Medical Emergency and taught to prehospital physicians and nurses at the time of enrollment in prehospital teams to ensure consistency in the treatment of trauma patients nationwide. The patients assigned to the intervention arm will receive the administration of a fixed dose of 4g fibrinogen, as per previous studies.

DRUG

Standard trauma care

Patients will be randomly assigned to receive either standard trauma care or standard trauma care plus administration of FC. The standard of care is determined by national guidelines on trauma, elaborated by the National Institute of Medical Emergency and taught to prehospital physicians and nurses at the time of enrollment in prehospital teams to ensure consistency in the treatment of trauma patients nationwide. The patients assigned to the intervention arm will receive the administration of a fixed dose of 4g fibrinogen, as per previous studies.

All Listed Sponsors
collaborator

Unidade Local de Saúde de São José

UNKNOWN

collaborator

Unidade Local de Saúde da Arrábida

UNKNOWN

collaborator

Unidade Local de Saúde de Santa Maria

UNKNOWN

collaborator

Unidade Local de Saúde Almada-Seixal

UNKNOWN

lead

Unidade Local de Saude do Arco Ribeirinho

OTHER_GOV

NCT06582420 - Pre-hospital Administration of Fibrinogen in Trauma-Induced Coagulopathy | Biotech Hunter | Biotech Hunter