Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns

NANot yet recruitingINTERVENTIONAL
Enrollment

554

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

July 1, 2031

Study Completion Date

July 1, 2033

Conditions
Cardiac Arrest
Interventions
PROCEDURE

CC+SI (Chest compression during sustained inflation)

CC+SI (Chest compression during sustained inflation)

PROCEDURE

3:1 C:V (3:1 Compression:Ventilation ratio)

"3:1 C:V Group (Control group - Standard of Care): Newborns randomized to 3:1 C:V will receive a CC rate of 90/min and 30 ventilations/min as per current resuscitation guidelines. The PIP used for the 30 inflations will also be 30cmH2O) as per current resuscitation guidelines. Every 60sec, a HR assessment as per neonatal guidelines will be performed to assess if HR is \<60/min - continue CC or \>60/min - stop CC (current standard of care). 3:1 C:V will be continued until ROSC."

Trial Locations (1)

Unknown

Royal Alexandra Hospital, Edmonton

All Listed Sponsors
lead

University of Alberta

OTHER

NCT06577818 - Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns | Biotech Hunter | Biotech Hunter