440
Participants
Start Date
November 21, 2024
Primary Completion Date
December 31, 2028
Study Completion Date
June 1, 2029
Methadone
Single-dose intraoperative intravenous methadone with initial dose at 0.15 mg/kg in children and 0.2 mg/kg in adolescents.
Fentanyl/Hydromorphone
Per routine care, given as needed
RECRUITING
Duke University Medical Center, Durham
Lead Sponsor
National Institutes of Health (NIH)
NIH
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Duke University
OTHER