Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum

PHASE4RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

September 2, 2024

Primary Completion Date

December 30, 2024

Study Completion Date

December 30, 2024

Conditions
Laparoscopic Cholecystectomy
Interventions
DRUG

Dexmedetomidine low-dose

The low-dose dexmedetomidine group received a 75 μg/h loading dose over 15 minutes, followed by 60 μg/h maintenance infusion intravenously.

DRUG

normal Saline

The control group received volume-matched 0.9% saline infusions at identical rates.

DRUG

Dexmedetomidine high-dose

The high-dose dexmedetomidine group received a 150 μg/h loading dose over 15 minutes, followed by 120 μg/h maintenance infusion intravenously.

Trial Locations (1)

350001

RECRUITING

Fujian Provincial Hospital, Fuzhou

All Listed Sponsors
lead

Fujian Provincial Hospital

OTHER

NCT06575179 - Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum | Biotech Hunter | Biotech Hunter