Quantification of Myocardial Fibrosis in Aortis Stenosis

Conventional transthoracic echocardiography will be performed, with added 3D-imaging and acquisitions with high frame rate. The data from these patients will be anonymized and transferred for post-hoc analysis in dedicated computer software (GE Vingmed, EchoPac 2.6) and in validated machine learning algorithms.

Cardiac MRI will be performed. In all patients without contraindications, a gadolinium-based contrast agent will be given.

Conventional brachial venous blood samples will be drawn. Hematocrit value {in %} will be used to calculate CMR-derived exttracellular volume (ECV)

ECG/Holter-ECG will be performed, and the findings will be related to the imaging findings.

6 MWT will be performed, and the findings will be related to findings from CMRI/echocardiography.