Analgesic Efficacy of an Opioid-free Postoperative Pain Management Strategy Versus a Conventional Opioid-based Strategy Following Video-assisted Thoracoscopic Lobectomy

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

June 30, 2025

Conditions
Postoperative Pain
Interventions
DRUG

Ropivacaine

300 mL of 0.25% ropivacaine, the mode was intermittent pumping, and the parameters were set as follows: 30 mL of the first dose, 5 mL/h of the background dose, and 10 mL of the pumping every 6h for the first 24 hours after the operation.

DRUG

Sufentanil

Sufentanil 2.0 μg/kg, 0.9% saline diluted to 100 mL, background dose of 2 ml/h, no loading dose, activated after extubation and continued until 48 hours postoperatively.

All Listed Sponsors
lead

Affiliated Cancer Hospital & Institute of Guangzhou Medical University

OTHER

NCT06570538 - Analgesic Efficacy of an Opioid-free Postoperative Pain Management Strategy Versus a Conventional Opioid-based Strategy Following Video-assisted Thoracoscopic Lobectomy | Biotech Hunter | Biotech Hunter