Preoperative Microbial Reduction of the Nasal Cavity With Antimicrobial Photodynamic Therapy (aPDT).

NANot yet recruitingINTERVENTIONAL
Enrollment

208

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

February 28, 2026

Study Completion Date

August 31, 2026

Conditions
Efficacy of Preoperative Microbial Reduction in the Nasal Cavity Using Antimicrobial Photodynamic Therapy (aPDT)
Interventions
DEVICE

activated Light Source (aPDT)

"Application of SW3100 Formulation (0.2% chlorhexidine gluconate and methylene blue) in both nostrils followed by placing the SW3200 Nasal Light Illuminator with one channel per nostril.~Activation of SW4000 Light Source (Class 1 Laser Device) that generates red light consisting of 2 channels of 700 mW, 664 nm light (continuous wave) used to activate the disinfecting formulation.~Duration of illumination 2 minutes"

DEVICE

non activated Light Source (Control)

"Application of SW3100 Formulation (0.2% chlorhexidine gluconate and methylene blue) in both nostrils followed by placing the SW3200 Nasal Light Illuminator with one channel per nostril.~No activation of SW4000 Light Source~Waiting for 2 minutes"

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Ondine Biomedical Inc.

INDUSTRY

collaborator

University Hospital, Zürich, Innovation Pool

UNKNOWN

lead

University of Zurich

OTHER