Pharmacogenomic Informed Statin Prescribing

NARecruitingINTERVENTIONAL
Enrollment

410

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

May 31, 2027

Study Completion Date

July 28, 2028

Conditions
Hypercholesterolemia
Interventions
GENETIC

Pharmacogenetic and polygenic risk testing

The intervention involves: genetic testing; interpretation; and prior to and shortly following an upcoming appointment, communication to patients and providers about the patients' predicted statin efficacy and toxicity, genetic risk for CVD, and individualized recommended statin type/dose.

OTHER

Active control

The control condition involves receipt of a report highlighting the risk of cardiovascular disease and benefits of statins (without genetic test

Trial Locations (2)

46202-2884

RECRUITING

Richard L. Roudebush VA Medical Center, Indianapolis, IN, Indianapolis

27705-3875

NOT_YET_RECRUITING

Durham VA Medical Center, Durham, NC, Durham

All Listed Sponsors
lead

VA Office of Research and Development

FED