Honokiol in Early-Stage Resectable Non-Small Cell Lung Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 8, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2027

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG

Honokiol

Honokiol will be given orally at a starting dose of 1 capsule (250 mg/ capsule) per day for 2 weeks. Dose levels will escalate based on dose-limiting toxicity occurrence. We will start at one capsule (250 mg) once daily, dose 0 would be one capsule (250 mg) twice daily, dose +1 would be 500mg in the AM and 250mg in the evening, and +2 would be 500 mg twice daily.

Trial Locations (1)

77030

RECRUITING

Houston Methodist Neal Cancer Center, Houston

All Listed Sponsors
lead

The Methodist Hospital Research Institute

OTHER