Oxfendazole in Mild Parenchymal Brain Cysticercosis

PHASE2/PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

544

Participants

Timeline

Start Date

December 15, 2024

Primary Completion Date

March 30, 2028

Study Completion Date

December 30, 2028

Conditions
Brain Cysticercosis
Interventions
DRUG

Oxfendazole single dose

Subjects will receive active oxfendazole, 20 mg/kg/day, orally, as a single dose. Oxfendazole placebo will be used at days 4 and 7 to maintain blinding between the two intervention arms.

DRUG

Oxfendazole three doses

Subjects will receive active oxfendazole, 20 mg/kg/day, orally, in three days (1, 4 and 7)

DRUG

albendazole plus praziquantel regime

Subjects will receive a combination of albendazole plus praziquantel, as a standard treatment for brain cysticercosis (neurocysticercosis), orally, for ten days. Albendazole will be given at 15/kg/d and praziquantel at 50/kg/d.

Sponsors
All Listed Sponsors
collaborator

Oxfendazole Development Group

OTHER

lead

Universidad Peruana Cayetano Heredia

OTHER

NCT06565507 - Oxfendazole in Mild Parenchymal Brain Cysticercosis | Biotech Hunter | Biotech Hunter