Lipiodol Prior to FET (LIFE)

NANot yet recruitingINTERVENTIONAL
Enrollment

784

Participants

Timeline

Start Date

August 10, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

December 31, 2026

Conditions
IVFFrozen Embryo TransferHysterosalpingography
Interventions
PROCEDURE

Lipiodol® uterine treatment prior to IVF/ICSI

Lipiodol®, treatment will be performed by a HSG technique with X-ray screening on day 3 or day 5 after oocyte retrieval. The contrast medium will be Lipiodol Ultra Fluide® (Guerbet, France), an iodized poppy seed oil obtained by substitution of ethyl esters for the glyceryl esters of Lipiodol®. One millilitre of Lipiodol Ultra Fluide® contains 0.48g iodine. Women will lie in the left lateral or supine position. Radiologists will use a 'no touch' technique after applying antiseptic solution to the cervix. Uterine cannulation using the Cook HSG catheter will be applied to conduct Lipiodol® treatment. Prewarmed (37oC) Lipiodol® will be slowly instilled, with intermittent fluoroscopic X-ray guidance. Up to 10 ml of Lipiodol® will be slowly injected into the uterus and directly monitored by fluoroscopy. If intravasation was observed on X-ray (contrast apparent in the venous system), instillation will be stopped immediately.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Guerbet

INDUSTRY

lead

Mỹ Đức Hospital

OTHER

NCT06563908 - Lipiodol Prior to FET (LIFE) | Biotech Hunter | Biotech Hunter