291
Participants
Start Date
August 19, 2024
Primary Completion Date
August 31, 2027
Study Completion Date
August 31, 2027
FMISO-PET Scan
Patients will undergo 18F-FMISO scan (only 1 injection) that occurs at week two of radiation treatment, typically day 10 but a window of 8-10 radiation treatment days\* after start of radiation is allowed.
Chemoradiation
30 Gy or 70 Gy of radiation in combination with standard chemotherapy (cisplatin, carboplatin, and 5-FU)
Chemoradiation
70 Gy of radiation in combination with standard chemotherapy (cisplatin, carboplatin, and 5-FU)
Assessments
EQ-5D-5L (5 questions); 2. MDADI-HN (total of 20 questions); 3. COST-FACIT (total of 12 questions).
RECRUITING
Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
RECRUITING
Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison
RECRUITING
Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale
RECRUITING
Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities), Commack
RECRUITING
Baptist Alliance MCI (Data Collection Only), Miami
RECRUITING
Hartford Healthcare (Data Collection Only), Hartford
RECRUITING
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge
RECRUITING
Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown
RECRUITING
Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale
Memorial Sloan Kettering Cancer Center
OTHER