A Study on the Efficacy of Disitamab Vedotin in Advanced HER2-positive Paget's Disease.

PHASE2RecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

August 15, 2024

Primary Completion Date

August 15, 2025

Study Completion Date

August 15, 2027

Conditions
Mammary or Extramammary Paget's Disease
Interventions
DRUG

RC48

RC48 at a dosage of 2mg/kg administered intravenously every 3 weeks (ivgtt q3w) is continued until disease progression, with the allowance for treatment discontinuation due to disease progression, death, intolerable toxicity, withdrawal of informed consent, initiation of new antineoplastic therapy, or other reasons specified in the protocol, with the earliest occurring event taking precedence. Alternatively, the study investigator may determine the need to discontinue treatment.

Trial Locations (1)

200032

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER