NCT06559995 - Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions

Alcohol Use DisorderAlcohol WithdrawalKetosis

Interventions

DIETARY_SUPPLEMENT

"ketone supplement D-beta-hydroxybutryric acid and R-1,3 butanediol 12g of ketones,"

ketone supplement

DIAGNOSTIC_TEST

magnetic resonance imaging session

1.5 hour magnetic resonance imaging session

DIETARY_SUPPLEMENT

Placebo beverage

Placebo beverage, visually matched, three times a day before meals, by mouth for 4 days plus 1 dose on day 5 for magnetic resonance imaging session visit.

Trial Locations (1)

19104

RECRUITING

Center for Studies of Addiction, Philadelphia

All Listed Sponsors

collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

University of Pennsylvania

OTHER