Diagnosis of Graft Pathology by TruGraf

RecruitingOBSERVATIONAL
Enrollment

471

Participants

Timeline

Start Date

July 20, 2024

Primary Completion Date

July 20, 2027

Study Completion Date

December 30, 2027

Conditions
Acute Graft Rejection
Interventions
GENETIC

TruGraf liver gene expression

Blood from the patients undergoing graft liver biopsy will be collected on the day of the liver biopsy, preferable prior to tissue collection or within 48 hours following the biopsy. Two specialized PaxGene tubes containing 2.5mL of blood each will be filled and will be sent to TGI laboratory in USA for processing, storage, and analysis using TGI's proprietary bioinformatics TruGraf will provide UHN with a Liver binary result: ACR or non-ACR. The results data will be batched and sent to UHN at agreed upon timepoints.

Trial Locations (1)

M5G 2N2

RECRUITING

Toronto General Hospital -UHN, Toronto

All Listed Sponsors
collaborator

Transplant Genomics, Inc.

INDUSTRY

lead

University Health Network, Toronto

OTHER

NCT06557564 - Diagnosis of Graft Pathology by TruGraf | Biotech Hunter | Biotech Hunter