Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

August 23, 2023

Primary Completion Date

July 1, 2025

Study Completion Date

January 1, 2026

Conditions
Edentulous Alveolar RidgePeri-ImplantitisPeri-implant MucositisProsthetic InfectionProsthetic Complication
Interventions
DEVICE

Dental Crown with Titanium-Abutment

Participants in this clinical trial will receive dental implants and single screw-retained crowns made from one of four different materials: titanium, PEEK (Polyetheretherketone), zirconia, or lithium disilicate (e.max). The implants will be placed in the posterior region of the mandible or maxillae. The study will evaluate the impact of these materials on peri-implant soft tissue health by measuring inflammatory markers in the peri-implant crevicular fluid and assessing clinical outcomes such as bleeding on probing and pocket depth at 3 and 6 months post-implantation.

DEVICE

Dental Crown with PEEK (Polyetheretherketone)-Abutment

Participants in this clinical trial will receive dental implants and single screw-retained crowns made from one of four different materials: titanium, PEEK (Polyetheretherketone), zirconia, or lithium disilicate (e.max). The implants will be placed in the posterior region of the mandible or maxillae. The study will evaluate the impact of these materials on peri-implant soft tissue health by measuring inflammatory markers in the peri-implant crevicular fluid and assessing clinical outcomes such as bleeding on probing and pocket depth at 3 and 6 months post-implantation.

DEVICE

Dental Crown with Zirconia-Abutment

Participants in this clinical trial will receive dental implants and single screw-retained crowns made from one of four different materials: titanium, PEEK (Polyetheretherketone), zirconia, or lithium disilicate (e.max). The implants will be placed in the posterior region of the mandible or maxillae. The study will evaluate the impact of these materials on peri-implant soft tissue health by measuring inflammatory markers in the peri-implant crevicular fluid and assessing clinical outcomes such as bleeding on probing and pocket depth at 3 and 6 months post-implantation.

DEVICE

Dental Crown with Lithium-Disilicate-Abutment (e.max)

Participants in this clinical trial will receive dental implants and single screw-retained crowns made from one of four different materials: titanium, PEEK (Polyetheretherketone), zirconia, or lithium disilicate (e.max). The implants will be placed in the posterior region of the mandible or maxillae. The study will evaluate the impact of these materials on peri-implant soft tissue health by measuring inflammatory markers in the peri-implant crevicular fluid and assessing clinical outcomes such as bleeding on probing and pocket depth at 3 and 6 months post-implantation.

Trial Locations (1)

01362

RECRUITING

VIC Clinic, Vilnius

All Listed Sponsors
lead

Harvard Medical School (HMS and HSDM)

OTHER