30
Participants
Start Date
November 20, 2024
Primary Completion Date
May 28, 2025
Study Completion Date
November 1, 2025
Nasal humidified heated high flow cannula (NHHHC)
Patients in this arm will receive humidified heated high flow using Vapotherm device, USA. Stating with 2 L/min flow and increase gradually till 8L/minute, guided by oxygen requirements.
Nasal intermittent positive pressure ventilation (NIPPV)
Patients in this arm will receive both PEEP (positive end expiratory pressure ) and PIP (peak inspiratory pressure) using SLE 5000/6000 device, UK . Pressures will be adjusted according to severity of respiratory distress.
Nasal continuous positive airway pressure NCPAP
Patients in this arm will receive PEEP (positive end expiratory pressure ), stating from 5 mbar to reach maximally 8 mbar.
lung ultrasound
Lung ultrasound (LUS) machine is a mobile device (Philips HDll XE, USA) with s8-3 probe with a frequency range of 8-3 MHz will be used as ultrasound machine. Throughout the period of non-invasive respiratory support Patient will be monitored by: LUS,Heart rate, Respiratory rate, Mean arterial pressure, Oxygen saturation index, Oxygen index, PaO2, blood gases and Fractional inspired oxygen (Fio2).
RECRUITING
Alexandria university, Elshattbi hospital, Alexandria
Alexandria University
OTHER