Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes

NARecruitingINTERVENTIONAL
Enrollment

324

Participants

Timeline

Start Date

August 19, 2024

Primary Completion Date

February 29, 2028

Study Completion Date

February 28, 2029

Conditions
Gestational Diabetes Mellitus in PregnancyGlucose Intolerance During PregnancyNon-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
Interventions
BEHAVIORAL

NNS Restriction Intervention

"Discuss current scientific literature surrounding NNS consumption, obesity, and chronic disease and the emerging evidence that consumption in pregnancy/lactation may have unfavorable effects on infants' adiposity and health.~Provide detailed handouts, which will include a list of specific foods and beverages containing NNS to avoid during the study and summarize current scientific evidence on the metabolic and health effects of NNS.~Emphasize that sugar is not the best alternative to NNS, and that the participant should drink still water, sparkling water, flavored waters with no added sweeteners, or unsweetened tea instead.~Bi-weekly shipments of unsweetened beverages of participant's choice to replace usual consumption of NNS containing beverages.~Automated text messages will also be sent to mothers once per week with reminders that they should avoid NNS"

BEHAVIORAL

Control Intervention

"Counsel about best practices for home safety and babyproofing.~Provide a detailed booklet to take home, which will provide information about home safety and baby proofing.~Educate about common causes of accidental infant and young child injuries or death.~Automated text messages will also be sent to mothers once per week with reminders about home safety, infant safety, and baby proofing."

Trial Locations (1)

20037

RECRUITING

The George Washington University, Washington D.C.

All Listed Sponsors
collaborator

Children's Hospital Los Angeles

OTHER

collaborator

Children's National Research Institute

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

George Washington University

OTHER

NCT06548828 - Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes | Biotech Hunter | Biotech Hunter