30
Participants
Start Date
January 1, 2024
Primary Completion Date
December 1, 2025
Study Completion Date
December 1, 2026
Zanubrutinib
160mg bid/d, from C1 to CR and MRD-negative or C24
Lenalidomide
From C3 dose escalation, all 3 dose groups climbed from 5 mg/d to 10 mg/d, 15 mg/d, and 20 mg/d respectively, Taking 21 days of medication and 7 days of rest, 1 cycle every 28 days to CR and MRD-negative or C24
Obinutuzumab
1000 mg C1, d1/d8/15; 1000 mg C2-6, d1
Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin
Institute of Hematology & Blood Diseases Hospital, China
OTHER