Study of Oral Weekly GS-1720 and GS-4182 Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed

PHASE2/PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

675

Participants

Timeline

Start Date

August 20, 2024

Primary Completion Date

January 31, 2028

Study Completion Date

June 30, 2029

Conditions
HIV-1-Infection
Interventions
DRUG

GS-1720

Tablets administered orally without regard to food

DRUG

GS-4182

Tablets administered orally without regard to food

DRUG

Placebo to Match BVY

Tablets administered orally without regard to food

DRUG

Bictegravir/emtricitabine/tenofovir alafenamide

Tablets administered orally without regard to food

DRUG

GS-1720/GS-4182 FDC

Tablets administered orally without regard to food

DRUG

Placebo to Match GS1720/GS-4182 FDC

Tablets administered orally without regard to food

Trial Locations (39)

10016

NYU Langone Health Vaccine Center, New York

11355

NewYork-Presbyterian Queens, Flushing

20007

Georgetown University Medical Center, Washington D.C.

28078

Rosedale Health and Wellness, Huntersville

30033

Metro Infectious Disease Consultants, P.L.L.C., Decatur

31201

Mercer University, Department of Internal Medicine, Macon

31401

Chatham County Health Department, Savannah

32720

Midland Florida Clinical Research Center, LLC, DeLand

32803

Orlando Immunology Center, Orlando

33016

Floridian Clinical Research, Miami Lakes

33133

AIDS Healthcare Foundation - The Kinder Medical Group, Miami

33316

CAN Community Health, Fort Lauderdale

33407

Triple O Research Institute, P.A., West Palm Beach

34237

CAN Community Health, Sarasota

34982

Midway and Immunology Research Center, Ft. Pierce

35294

UAB 1917 Research Clinic, Birmingham

48072

Be Well Medical Center, Berkley

64111

KC CARE Health Center, Kansas City

75215

Prism Health North Texas, Oak Cliff Health Center, Dallas

75246

North Texas Infectious Diseases Consultants, PA, Dallas

75605

DCOL Center for Clinical Research, Longview

76104

Texas Centers for Infectious Disease Associates, Fort Worth

77098

The Crofoot Research Center, INC., Houston

77401

St Hope Foundation, Inc., Bellaire

78705

Central Texas Clinical Research, Austin

79902

AXCES Research Group, LLC, El Paso

87505

AXCES Research Group, LLC, Santa Fe

90036

Ruane Clinical Research Group, Los Angeles

90069

Mills Clinical Research, Los Angeles

90211

Pacific Oaks Medical Group, Beverly Hills

90502

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance

92262

BIOS Clinical Research, Palm Springs

94110

UCSF Division of HIV, Infectious Diseases & Global Medicine, San Francisco

98104

Peter Shalit, MD, Seattle

07102

Saint Michael's Medical Center, Newark

00717

Centro Ararat, Inc., San Juan

00909-1711

Clinical Research Puerto Rico, San Juan

00909

HOPE Clinical Research, San Juan

00935

Proyecto ACTC, San Juan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY

NCT06544733 - Study of Oral Weekly GS-1720 and GS-4182 Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed | Biotech Hunter | Biotech Hunter