Safety and Efficacy of AR1005 in Patients with Lewy Body Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Lewy Body Dementia
Interventions
DRUG

AR1005

AR1005 inhibits sodium currents by selective binding to the inactive sodium channel, suppressing the release of the excitatory amino acid, glutamate.

DRUG

Placebo

Matching placebo for AR1005 to be administered BID for 20 weeks

DRUG

Rivastigmine 3 mg

3mg Rivastigmine will be administered BID for both active and placebo groups

Trial Locations (1)

03722

RECRUITING

Severance Hospital, Seoul

All Listed Sponsors
collaborator

Samjin Pharmaceutical Co., Ltd.

INDUSTRY

collaborator

AriBio Co., Ltd.

INDUSTRY

lead

Yonsei University

OTHER

NCT06537076 - Safety and Efficacy of AR1005 in Patients with Lewy Body Disease | Biotech Hunter | Biotech Hunter