Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

July 31, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

May 31, 2026

Conditions
Carcinoma, Hepatocellular
Interventions
PROCEDURE

Cryoablation

After the completion of screening, the subjects received cryoablation treatment

DRUG

PD-1 antibody and bevacizumab

Three days after cryoablation, the patients receive intravenous infusion of Tislelizumab (200mg, with 100mL of normal saline) and Bevacizumab (dose 15mg/kg, with 100mL of normal saline) .The patients will receive Tislelizumab (200 mg, with 100 mL of normal saline) and Bevacizumab (15 mg/kg, with 100 mL of normal saline) once every 3 weeks until disease progression.

Trial Locations (1)

200032

Zhongshan Hospital, Fudan University, Shanghai

All Listed Sponsors
lead

Shanghai Zhongshan Hospital

OTHER