PI3K Inhibitors for the Treatment of Relapsed/Refractory Indolent T/NK-cell Lymphomas

PHASE2RecruitingINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

August 10, 2024

Primary Completion Date

August 10, 2026

Study Completion Date

July 10, 2028

Conditions
Lymphoma, T-CellNK-LGL LeukemiaT-LGL Leukemia
Interventions
DRUG

PI3K inhibitor

Linperlisib 80mg QD orally, or Duvelisib 25mg BID orally, with a 28-day cycle. Efficacy will be evaluated once per cycle during the first year, and once every two cycles thereafter. Treatment will continue for up to 24 cycles, or until disease progression, lack of response within the first 6 cycles, or the occurrence of intolerable toxicity, whichever occurs first

Trial Locations (1)

300020

RECRUITING

Institute of Hematology & Blood Diseases Hospital, Tianjin

All Listed Sponsors
lead

Institute of Hematology & Blood Diseases Hospital, China

OTHER