Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

640

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

September 30, 2026

Conditions
Critical CareAcute Hypoxic Respiratory FailureVentilator-Induced Lung Injury
Interventions
PROCEDURE

PMI-targeted pressure support setting and adjustment

During PSV, the pressure support is set and adjusted to a PMI target between 0 and 2 cmH2O.

PROCEDURE

VT/RR-targeted pressure support setting and adjustment

During PSV, pressure support is set and adjusted according to a VT/RR target of VT between 6 and 8 ml/kg predicted body weight, RR between 20 and 35 breaths/min, and no signs of respiratory distress.

Trial Locations (1)

100038

Beijing Shijitan Hospital, Beijing

All Listed Sponsors
lead

Capital Medical University

OTHER