A Study of CT-388 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

450

Participants

Timeline

Start Date

August 16, 2024

Primary Completion Date

January 17, 2026

Study Completion Date

February 21, 2026

Conditions
ObesityOverweight
Interventions
DRUG

Placebo

Placebo will be volume- matched and administered subcutaneously (SC) once weekly.

DRUG

CT-388

CT-388 will be administered subcutaneously (SC) once weekly at the randomized dosing regimen.

Trial Locations (34)

11516

Neurobehavioral Research, Inc. (NBR), Cedarhurst

23294

National Clinical Research - Richmond, Inc, Richmond

28557

Lucas Research, Inc, Morehead City

29607

Tribe Clinical Research, Greenville

32127

Progressive Medical Research, Port Orange

33761

Tampa Bay Medical Research, Inc., Clearwater

35209

Central Alabama Research, Homewood

35235

Alabama Clinical Therapeutics, LLC, Birmingham

37203

Clinical Research Associates, Inc., Nashville

37920

Alliance for Multispecialty Research, LLC, Knoxville

40213

Louisville Metabolic and Atherosclerosis Research Center (L-MARC), Louisville

45242

Velocity Clinical Research - Cincinnati, Cincinnati

59701

Mercury Street Medical Group, Butte

64114

The Center for Pharmaceutical Research, Kansas City

75230

Velocity Clinical Research - Dallas, Dallas

75231

FutureSearch Trials of Dallas, LLC, Dallas

75390

University of Texas Southwestern, Dallas

76710

Impact Research Institute, Waco

77401

Apex Mobile Clinical Research, Bellaire

77586

Elevate Clinical, Seabrook

78229

Pinnacle Clinical Research, San Antonio

78731

Texas Diabetes & Endocrinology, P.A., Austin

84790

Chrysalis Clinical Research, St. George

85210

The Institute for Liver Health II LLC dba Arizona Clinical Trials; Arizona Liver Health, Mesa

90057

Velocity Clinical Research - Los Angeles, Los Angeles

90806

Ark Clinical Research - Long Beach, Long Beach

91307

Amicis Research Center - West Hills, West Hills

91324

Amicis Research Center, Northridge

91730

Prospective Research Innovations Inc., Rancho Cucamonga

92708

Ark Clinical-Fountain Valley, Fountain Valley

92780

Orange County Research Center, Tustin

92801

Amicis Research Center - Anaheim, Anaheim

92860

Infinity Clinical Research, Norco

02818

Velocity Clinical Research, Providence, East Greenwich

Sponsors
All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Carmot Therapeutics, Inc.

INDUSTRY