Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial

PHASE2Enrolling by invitationINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

August 1, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Cervical Intraepithelial NeoplasiaTrichloroacetic Acid
Interventions
DRUG

85%TCA topical application

85%TCA topical application is done at cervical lesion and transformation zone. Application of TCA will be guided by colposcopy using a small cotton-tipped applicators and wooden end of the applicators. A thin film of TCA will be applied to cover the lesion and transformation zone.

DRUG

3% acetic acid

3% acetic acid topical application is done at cervical lesion and transformation zone. Application will be guided by colposcopy using a small cotton-tipped applicators and wooden end of the applicators. A thin film of acetic acid will be applied to cover the lesion and transformation zone.

Trial Locations (1)

10400

Rajavithi Hospital, Thailand

All Listed Sponsors
lead

Department of Medical Services Ministry of Public Health of Thailand

OTHER_GOV