Initial Resuscitation for Acute Kidney Injury in Cirrhosis

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 12, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Cirrhosis, LiverAcute Kidney InjuryHepatorenal Syndrome
Interventions
OTHER

Recommendation: No Further Resuscitation

Treatment teams are encouraged not to administer any additional fluids

OTHER

Recommendation: Resuscitation with Crystalloid

Treatment teams are encouraged to administer crystalloid. Amount of resuscitative fluid will be determined by treatment team's clinical assessments and usual standards of care

OTHER

Recommendation: Resuscitation with Colloid

Treatment teams are encouraged to administer colloid. Amount of resuscitative fluid will be determined by treatment team's clinical assessments and usual standards of care

OTHER

Recommendation: Standard of Care IV Albumin

Treatment teams are encouraged to administer 1 g/kg/d IV albumin (maximum 100 g/day) over 2 days

Trial Locations (1)

02114

RECRUITING

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Massachusetts General Hospital

OTHER