35
Participants
Start Date
July 23, 2024
Primary Completion Date
December 1, 2026
Study Completion Date
December 1, 2026
Neoadjuvant SBRT combined with Lenvatinib and Pucotenlimab
"SBRT: SBRT will be performed within 2-4 weeks after enrollment. The total radiation dose will be 24 Gy, delivered in 3 fractions on alternate days, to be completed within one week.~Lenvatinib: 8mg/day, begin immediately after enrollment. Lenvatinib should be discontinued one week before surgery.~Pucotenlimab: 200mg,3-week interval between cycles, begin immediately after enrollment, a total of four cycles of Puco treatment must be completed before surgery.~Surgical resection will be performed within 10-16 weeks after the completion of SBRT."
Sun Yat-sen University Cancer Center, Guangzhou
Sun Yat-sen University
OTHER