Intratonsillar Immunotherapy for Allergic Rhinitis

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

April 29, 2024

Primary Completion Date

April 29, 2028

Study Completion Date

April 29, 2028

Conditions
Allergic Rhinitis
Interventions
PROCEDURE

Intratonsillar immunotherapy (ITIT)

During injection, the operator needs to gently shake the injection bottle about 20 times, the drug must be mixed to ensure the consistency of allergen concentration, and carefully check the patient's name and concentration on the bottle. Allergy extracts should not be injected intravenously, so the syringe will be aspirated to avoid inadvertent intravascular injection. Before each injection, after inserting the needle into the selected tonsil, before injecting the dose, the investigator will slightly pull the plunger of the syringe. If blood returns from the syringe, the syringe, and its contents will be discarded. The other tonsil will be selected and a new syringe will be prepared.

PROCEDURE

Subcutaneous immunotherapy (SCIT)

Injection requires shaking bottle 20x to mix drug for consistency. Verify patient name \& concentration. Use 1 ml skin test syringe for deep subcutaneous injection at 45° angle, 1 cm into outer upper arm. Lift skin folds for deeper injection, avoid subcutaneous, muscular or intravascular. Inject slowly, 1 min for 1 ml. Avoid shallow injections which may cause local side effects. Alternate between left \& right arm for 5 min after injection for compression.

Trial Locations (1)

430060

RECRUITING

Renmin Hospital of Wuhan University, Wuhan

All Listed Sponsors
lead

Xu Yu

OTHER