A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

PHASE1RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

July 18, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Locally Advanced Solid TumorMetastatic Solid Tumor
Interventions
DRUG

NVL-330

Oral Tablet of NVL-330

Trial Locations (21)

2065

RECRUITING

North Shore Health Hub, Saint Leonards

10065

RECRUITING

Memorial Sloan Kettering Cancer Center, New York

20007

RECRUITING

Georgetown University Medical Center, Washington D.C.

20016

RECRUITING

Sibley Memorial Hospital, Washington D.C.

21224

RECRUITING

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Bayview Medical Center, Baltimore

22031

RECRUITING

NEXT Virginia, Fairfax

33136

RECRUITING

Sylvester Comprehensive Cancer Center, Miami

37203

RECRUITING

SCRI Oncology Partners, Nashville

43210

RECRUITING

OSU Brain and Spine Hospital, Columbus

48242

RECRUITING

Henry Ford Cancer Center, Detroit

63110

RECRUITING

Washington University, St Louis

77030

RECRUITING

The University of Texas MD Anderson Cancer Center, Houston

80218

RECRUITING

Sarah Cannon Research Institute at HealthONE, Denver

92618

RECRUITING

City of Hope - Lennar, Irvine

94305

RECRUITING

Stanford Cancer Institute, Stanford

95817

RECRUITING

University of California, Davis Comprehensive Cancer Center, Sacramento

98109

RECRUITING

Fred Hutchinson Cancer Center, Seattle

02114

RECRUITING

Massachusetts General Hospital, Boston

NSW 2050

RECRUITING

Chris O'Brien Lifehouse, Camperdown

T6G 1Z2

RECRUITING

Cross Cancer Institute, Edmonton

M5G 1L7

RECRUITING

Princess Margaret Cancer Center - University Health Network, Toronto

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Nuvalent Inc.

INDUSTRY

NCT06521554 - A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1) | Biotech Hunter | Biotech Hunter