Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

November 1, 2024

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2034

Conditions
MyelomaMultiple MyelomaRefractory Multiple Myeloma
Interventions
DRUG

Elotuzumab

Humanized, recombinant IgG1 monoclonal antibody, 400- and 300-mg single-use vials, via intravenous (into the vein) infusion per protocol.

DRUG

Iberdomide

A cereblon E3 ligase modulator, 0.15mg, 0.2mg, 0.3mg, 0.45mg, 0.6, and 0.75 mg strength capsule taken orally per protocol.

DRUG

Dexamethasone

Synthetic adrenocortical steroid, 2 and 4 mg tablets, taken orally per standard of care.

Trial Locations (3)

02115

NOT_YET_RECRUITING

Brigham and Women's Hospital, Boston

02215

NOT_YET_RECRUITING

Beth Israel Deaconess Medical Center, Boston

RECRUITING

Dana Farber Cancer Institute, Boston

Sponsors
All Listed Sponsors
collaborator

Celgene

INDUSTRY

collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Omar Nadeem, MD

OTHER