Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 9, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2027

Conditions
Multiple MyelomaPlasma Cell Leukemia
Interventions
DRUG

Isatuximab

Subcutaneous isatuximab will be administered weekly on a 28-day cycle during the first two cycles, and every two weeks of a 28-day cycle thereafter. Dexamethasone will be administered on the days of isatuximab administration and can be discontinued after two cycles of therapy, or continued at discretion of investigator. Lenalidomide, will be added after two cycles of therapy have been completed.

Trial Locations (1)

84112

RECRUITING

Huntsman Cancer Institute at the University of Utah, Salt Lake City

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

lead

University of Utah

OTHER