NCT06515860View on ClinicalTrials.gov

Neurofibromatosis Type 1 Tumor Early Detection Study

RecruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

August 7, 2024

Primary Completion Date

July 31, 2030

Study Completion Date

July 31, 2030

Conditions
Neurofibromatosis Type 1Neurofibromatosis 1Plexiform NeurofibromaPlexiform NeurofibromasMalignant Peripheral Nerve Sheath TumorMalignant Peripheral Nerve Sheath TumorsAtypical Neurofibroma
Interventions
DIAGNOSTIC_TEST

Liquid biopsy for MPNST development

Participants will be asked to complete a blood sample (liquid biopsy) at baseline (15 mL, approximately 1 tablespoon) and every 6 months (10 mL) for the five-year follow-up period.

Trial Locations (1)

02115

RECRUITING

Boston Children's Hospital, Boston

All Listed Sponsors
lead

David Miller

OTHER