Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib.

PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 18, 2025

Primary Completion Date

December 1, 2028

Study Completion Date

December 1, 2028

Conditions
Chronic Myeloid Leukemia (CML)
Interventions
DRUG

ABL001/Asciminib

"The study treatment for this clinical trial is an investigational drug called asciminib, which is marketed under the brand name Scemblix®. Asciminib is a compound that is being evaluated for its efficacy and safety in the treatment of the target condition.~The minimum dose of asciminib to be administered in this study is 200 mg, while the maximum dose is 400 mg. The dose is planned as 200 mg twice a day (BID).~The drug will be administered orally, allowing for convenient and non-invasive administration."

Trial Locations (2)

44093

RECRUITING

Novartis Investigative Site, Nantes

69373

RECRUITING

Novartis Investigative Site, Lyon

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY