Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 30, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

December 31, 2026

Conditions
Multiple Myeloma
Interventions
DRUG

Motixafortide+G-CSF

Patients will receive the first dose of motixafortide (1.25 mg/kg) by subcutaneous (SC) injection on the evening of Day 4 (10 to 14 hours) prior to initiation of the first apheresis. A second dose of motixafortide can be administered 10 to 14 hours before a third apheresis, if necessary for patients who did not reach the goal of collection. Injections of G-CSF per standard of care.

DRUG

Placebo+G-CSF

Patients will receive the first dose of placebo by subcutaneous (SC) injection on the evening of Day 4 (10 to 14 hours) prior to initiation of the first apheresis. A second dose of placebo can be administered 10 to 14 hours before a third apheresis, if necessary for patients who did not reach the goal of collection. Injections of G-CSF per standard of care.

Trial Locations (2)

100044

Peking University People's Hospital, Beijing

150010

Harbin The First Hospital, Harbin

All Listed Sponsors
lead

Guangzhou Gloria Biosciences Co., Ltd.

INDUSTRY

NCT06514508 - Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients | Biotech Hunter | Biotech Hunter