Second Haplo-transplantation for Graft Failure

NARecruitingINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

July 1, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2027

Conditions
Graft FailureStem Cell Transplant Complications
Interventions
OTHER

second allogeneic stem cell transplantation

"1. Change another donor if possible~2. Conditioning regimen: fludarabine (30mg/m2/day, days -6 to -2 ), cyclophosphamide (1g/m2/day, days -5 to -4)~3. GVHD prophylaxis: cyclosporine A (concentration 150-250ng/ml), mycophenolate mofetil (0.5g bid -3d to neutrophil engraftment)+anti CD25 monoAb (20mg -1d, +4d, +15d)"

Trial Locations (1)

100044

RECRUITING

Peking University People's Hospital, Beijing

All Listed Sponsors
collaborator

The First Affiliated Hospital of Soochow University

OTHER

collaborator

Ruijin Hospital

OTHER

collaborator

Zhejiang University

OTHER

collaborator

First Affiliated Hospital of Xinjiang Medical University

OTHER

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

Guangdong Provincial Hospital of Traditional Chinese Medicine

OTHER

collaborator

First Affiliated Hospital of Fujian Medical University

OTHER

collaborator

Hebei Yanda Ludaopei Hospital

OTHER

collaborator

Tongji Hospital

OTHER

collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Peking University First Hospital

OTHER

collaborator

Jiangsu Provincial People's Hospital

OTHER

collaborator

Shengjing Hospital

OTHER

collaborator

Xinqiao Hospital of Chongqing

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

First Affiliated Hospital of Guangxi Medical University

OTHER

collaborator

Anhui Provincial Hospital

OTHER_GOV

lead

Peking University People's Hospital

OTHER