A Clinical Trial of SIBP-A17 Injection in the Treatment of Advanced Solid Tumor Patients.

PHASE1RecruitingINTERVENTIONAL
Enrollment

196

Participants

Timeline

Start Date

July 23, 2024

Primary Completion Date

July 30, 2025

Study Completion Date

December 30, 2025

Conditions
Advanced Solid Tumor
Interventions
DRUG

SIBP-A17

"Strength: 1, 2, 4, 5, 6 or 8 mg. Intravenous infusion administration, with a treatment cycle of every 21 days, administered once on the first day of each cycle.~The dose escalation stage, 1mg/kg and 2mg/kg were subjected to accelerated titration, where the safety was evaluated within 21 days after the first administration to one subject. If dose-limiting toxicity (DLT) occurred, the traditional 3+3 dose escalation method was immediately switched. If DLT does not occur, the next dose group will be explored, and the dose exploration starting from 4mg/kg will adopt a 3+3 dose escalation design."

Trial Locations (1)

Unknown

RECRUITING

Cancer Hospital of Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing

All Listed Sponsors
lead

Shanghai Institute Of Biological Products

INDUSTRY