196
Participants
Start Date
July 23, 2024
Primary Completion Date
July 30, 2025
Study Completion Date
December 30, 2025
SIBP-A17
"Strength: 1, 2, 4, 5, 6 or 8 mg. Intravenous infusion administration, with a treatment cycle of every 21 days, administered once on the first day of each cycle.~The dose escalation stage, 1mg/kg and 2mg/kg were subjected to accelerated titration, where the safety was evaluated within 21 days after the first administration to one subject. If dose-limiting toxicity (DLT) occurred, the traditional 3+3 dose escalation method was immediately switched. If DLT does not occur, the next dose group will be explored, and the dose exploration starting from 4mg/kg will adopt a 3+3 dose escalation design."
RECRUITING
Cancer Hospital of Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing
Shanghai Institute Of Biological Products
INDUSTRY