Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC

PHASE2RecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

April 11, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2028

Conditions
Esophageal Squamous Cell CarcinomaImmunotherapyBiomarkers
Interventions
DRUG

adebrelimab

The study was divided into two cohorts based on CPS score, with those with CPS scores ≥10 receiving induction therapy with adebrelimab alone and those with CPS scores \<10 receiving induction therapy with adebrelimab in combination with chemotherapy. At the end of the induction period, concurrent radiotherapy treatment was administered

Trial Locations (1)

350001

RECRUITING

Fujian Medical University Union Hospital, Fuzhou

All Listed Sponsors
collaborator

Sun Yat-sen University

OTHER

lead

Fujian Medical University Union Hospital

OTHER