Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction

NARecruitingINTERVENTIONAL
Enrollment

164

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Parenteral NutritionGastroparesisGastrointestinal DysfunctionProtein DeficiencyCritical Illness
Interventions
DIETARY_SUPPLEMENT

Supplemental Parenteral Nutrition (SPN)

Nutritional targets are based on ESPEN guidelines recommendation (calories administration based on indirect calorimetry study, proteins 1.3 g/kg/day). From the first day of ICU admission indirect calorimetry will be performed daily in order to evaluate energy requirements. On the fourth day, the patient will undergo a gastric residual volume measurement and a paracetamol absorption test. If gastrointestinal dysfunction is detected, the patient will be assigned to a study group based on the randomization protocol. The SPN group will gradually initiate supplemental parenteral nutrition in order to achieve the target of 80% by the fifth day. Trophic feed will be administered to cover the remaining 20% of the targeted nutrition intake.

Trial Locations (1)

Unknown

RECRUITING

Clinical Emergency Hospital of Bucharest, Bucharest

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Fresenius Kabi

INDUSTRY

collaborator

Carol Davila University of Medicine and Pharmacy

OTHER

collaborator

Bucharest Emergency Hospital

OTHER

lead

Romanian Society for Enteral and Parenteral Nutrition

OTHER

NCT06510348 - Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction | Biotech Hunter | Biotech Hunter