164
Participants
Start Date
October 1, 2024
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
Supplemental Parenteral Nutrition (SPN)
Nutritional targets are based on ESPEN guidelines recommendation (calories administration based on indirect calorimetry study, proteins 1.3 g/kg/day). From the first day of ICU admission indirect calorimetry will be performed daily in order to evaluate energy requirements. On the fourth day, the patient will undergo a gastric residual volume measurement and a paracetamol absorption test. If gastrointestinal dysfunction is detected, the patient will be assigned to a study group based on the randomization protocol. The SPN group will gradually initiate supplemental parenteral nutrition in order to achieve the target of 80% by the fifth day. Trophic feed will be administered to cover the remaining 20% of the targeted nutrition intake.
RECRUITING
Clinical Emergency Hospital of Bucharest, Bucharest
Collaborators (1)
Fresenius Kabi
INDUSTRY
Carol Davila University of Medicine and Pharmacy
OTHER
Bucharest Emergency Hospital
OTHER
Romanian Society for Enteral and Parenteral Nutrition
OTHER