The Tatelo Plus Study

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

41

Participants

Timeline

Start Date

November 11, 2024

Primary Completion Date

November 5, 2027

Study Completion Date

April 21, 2028

Conditions
HIVHIV Infections
Interventions
DRUG

PGDM1400LS

IV Antibody Infusion based on subject's weight

DRUG

VRC07-523LS

IV Antibody Infusion based on subject's weight

DRUG

PGT121.414.LS

IV Antibody Infusion based on subject's weight

DRUG

ART Regimen prior to enrolling in Step 1a

Antiviral drugs are not study product. However, participants will continue to receive the ART regimen they were receiving prior to enrolling in the study during Step 1a.

DRUG

ART Regimen prior to enrolling in Step 1b

Antiviral drugs are not study product. However, participants will continue to receive the ART regimen they were receiving prior to enrolling in the study during Step 1b.

OTHER

Analytic Treatment Interruption

(all anti-HIV agents are discontinued)

Trial Locations (2)

Unknown

RECRUITING

Francistown CRS (CRS #31891), Francistown

RECRUITING

Botswana Harvard Health Partnership CRS (CRS #31833), Gaborone

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH