NCT06508463 - Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 5, 2024

Primary Completion Date

December 31, 2028

Study Completion Date

April 1, 2032

Conditions

Peripheral T Cell LymphomaRelapsed Peripheral T-Cell LymphomaPeripheral T-Cell Lymphoma, Not Otherwise SpecifiedAnaplastic Large Cell LymphomaMycosis FungoidesRelapsed Anaplastic Large Cell LymphomaRelapsed Mycosis Fungoides

Interventions

PROCEDURE

Biopsy

Undergo tumor biopsy

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Bone Marrow Biopsy

Undergo bone marrow biopsy

PROCEDURE

Computed Tomography

Undergo SPECT/CT

PROCEDURE

Positron Emission Tomography

Undergo PET scan

BIOLOGICAL

Recombinant Vesicular Stomatitis Virus-expressing Human Interferon Beta and Sodium-Iodide Symporter

Given IV

PROCEDURE

Single Photon Emission Computed Tomography

Undergo SPECT/CT

BIOLOGICAL

Cemiplimab

Given IV

BIOLOGICAL

Ipilimumab

Given IV

Trial Locations (2)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

85259

RECRUITING

Mayo Clinic in Arizona, Scottsdale