Cryoballoon/Radiofrequency Ablation of Atrial Fibrillation Versus Medical Treatment for Heart

NANot yet recruitingINTERVENTIONAL
Enrollment

1,200

Participants

Timeline

Start Date

September 15, 2024

Primary Completion Date

December 15, 2031

Study Completion Date

December 15, 2031

Conditions
Atrial Fibrillation (AF)
Interventions
PROCEDURE

Catheter Ablation

Participants randomised to the catheter ablation arm will undergo Pulmonary Vein Isolation (PVI) which is the essential ablation intervention. The technique used will be at the discretion of the treating physician but may include Cryoballoon (Medtronic/Boston Scientific), Radiofrequency: CARTO (Biosense), pulsed field radiofrequency ablation, or Precision (Abbott Medical) electro-anatomical mapping systems. Additional ablation lesions may be delivered as preferred by the operator and will be documented. Electro-anatomical voltage maps will be collected (in SR/AF) and stored for later analysis.

All Listed Sponsors
lead

University College, London

OTHER

NCT06505798 - Cryoballoon/Radiofrequency Ablation of Atrial Fibrillation Versus Medical Treatment for Heart | Biotech Hunter | Biotech Hunter