[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2029

Conditions
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma
Interventions
OTHER

Best Practice

Receive of standard care

PROCEDURE

Biopsy of Breast

Undergo breast biopsy

PROCEDURE

Computed Tomography

Undergo FDG PET/CT

OTHER

Electronic Health Record Review

Ancillary studies

OTHER

Fludeoxyglucose F-18

Given FDG

RADIATION

Fluorine F 18 Fluorthanatrace

Given IV

DRUG

Immune Checkpoint Inhibitor

Receive ICI treatment

DRUG

Poly (ADP-Ribose) Polymerase Inhibitor

Receive PARP inhibitor treatment

PROCEDURE

Positron Emission Tomography

Undergo \[18F\]FTT PET

PROCEDURE

Positron Emission Tomography

Undergo FDG PET/CT

Trial Locations (1)

98109

Fred Hutch/University of Washington Cancer Consortium, Seattle

Sponsors
All Listed Sponsors
collaborator

Breast Cancer Research Foundation

OTHER

lead

University of Washington

OTHER