NCT06501482View on ClinicalTrials.gov

Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI

PHASE3Not yet recruitingINTERVENTIONAL

Enrollment

254

Participants

Timeline

Start Date

September 30, 2024

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2030

Conditions

Colorectal CancerColorectal Liver Metastases

Interventions

DRUG

Postoperative reintroduction of FOLFIRI based chemotherapy

Postoperative reintroduction of FOLFIRI: irinotecan 180 mg/m2 + leucovorin 400 mg/m2 at day 1 then 5-FU 400 mg/m2 bolus followed by 2400 mg/m2 continuous infusion over 46 h biweekly. For a total of 12 cycles of perioperative chemotherapy including the preoperative chemotherapy

Trial Locations (1)

75010

Hôpital Kremlin Bicêtre, Paris

All Listed Sponsors

lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT06501482 - Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI | Biotech Hunter | Biotech Hunter