PREMAPROB. Probiotics to Prevent Necrotizing Enterocolitis

NACompletedINTERVENTIONAL
Enrollment

583

Participants

Timeline

Start Date

January 10, 2015

Primary Completion Date

January 15, 2015

Study Completion Date

March 20, 2020

Conditions
Premature InfantsNecrotizing Enterocolitis
Interventions
DIETARY_SUPPLEMENT

High dose group

A daily high dose of a mixture of probiotics (Lactobacillus Fermentum CECT 5716 and Bifidobacterium breve CECT 7263), was given orally starting in the first 72 hours of life, until 36+6 weeks of postmenstrual age or discharge The total dose was 1x109 CFU of each of the strains

DIETARY_SUPPLEMENT

Low dose group

A daily low dose of a mixture of probiotics (Lactobacillus Fermentum CECT 5716 and Bifidobacterium breve CECT 7263), was given orally starting in the first 72 hours of life, until 36+6 weeks of postmenstrual age or discharge The total dose was 1x106 CFU of each of the strains

Trial Locations (1)

18012

Hospital Virgen de las Nieves, Granada

All Listed Sponsors
collaborator

University Hospital Virgen de las Nieves

OTHER

collaborator

Hospital Regional de Malaga

OTHER

collaborator

Hospital of Jaen

OTHER

collaborator

Hospital Costa del Sol

OTHER

collaborator

Hospital Universitario Torrecárdenas

OTHER

collaborator

Hospital Universitario Virgen Macarena

OTHER

collaborator

Complejo Hospitalario de Especialidades Juan Ramón Jimenez

OTHER

collaborator

Hospital Universitario de Valme

OTHER

collaborator

Hospitales Universitarios Virgen del Rocío

OTHER

collaborator

Hospital Universitario Puerta del Mar

OTHER

collaborator

Hospital General Universitario Santa Lucia

OTHER

collaborator

Hospital del SAS de Jerez

OTHER

lead

José Antonio Hurtado Suazo

OTHER

NCT06501404 - PREMAPROB. Probiotics to Prevent Necrotizing Enterocolitis | Biotech Hunter | Biotech Hunter